Inter Milan v Barcelona Prediction & Betting Tips

May 5, 2025
3 Minute Read

Tuesday | 19:00 UTC | San Siro | UEFA Champions League Semi-Final, 2nd Leg

With the tie locked at 3–3 after a pulsating first leg, Inter Milan and Barcelona collide in what promises to be a dramatic decider at the San Siro. Both clubs have one foot in Munich, but only one will cross the line, and recent history suggests the Italians have the edge.

Inter Milan v Barcelona Analysis

Simone Inzaghi’s Inter Milan have developed a reputation for delivering in high-pressure European nights, and they’ll need every ounce of that composure to see off Barcelona at home. The Nerazzurri led three times in Catalonia but were ultimately pegged back by a relentless Barça attack.

Despite squandering the advantage, a 3–3 draw at the Olympic Stadium represents a positive result, and one they would’ve taken gladly before kick-off. Inter now return to a ground where they’ve gone unbeaten against Barcelona in their last two visits, including a gritty 1–0 win in 2023.

Without Lautaro Martinez, who limped off in the first leg with a hamstring injury, the hosts will look to Marcus Thuram and the experience of Henrikh Mkhitaryan and Hakan Calhanoglu to carry the load.

Inter Milan v Barcelona Analysis

Barcelona were moments away from defeat last week, but the emergence of Lamine Yamal, still just 17, changed the narrative. His stunning goal and near-spectacular second (that rattled the crossbar) served notice to the football world: this kid is special.

With Robert Lewandowski expected to return for the second leg, they’ve got added firepower to complement the creative spark of Dani Olmo and the ever-dangerous Raphinha. Even so, they’ll need to be more secure at the back, conceding 3 at home in a semi-final isn’t the mark of European champions.

Inter Milan v Barcelona Odds

Barcelona are narrow 2.18 favourites to win the second leg despite playing away from home. Inter Milan are 3.00, while a draw, which would force extra time, is 3.85.

Head-to-Head: Inter Milan v Barcelona

These sides have become familiar foes in recent Champions League campaigns, and Inter have avoided defeat in their last three meetings with Barcelona. Two 3–3 draws and a 1–0 home win suggest Inzaghi’s men know exactly how to manage this matchup, especially on Italian soil.

Inter Milan v Barcelona Players to Watch

Lamine Yamal took centre stage last week and is capable of deciding this tie on his own. If he shines again, Barcelona could be Champions League finalists.

Marcus Thuram, stepping in for Lautaro, has the pace and power to trouble the Barça backline and is priced at 2.60 to score anytime.

Calhanoglu and Mkhitaryan will need to combine their tactical nous and experience to manage Barcelona’s midfield runners and limit Yamal’s space.

Inter Milan v Barcelona Predicted Lineups

Inter Milan: Sommer; Bisseck, Acerbi, Bastoni; Dumfries, Calhanoglu, Barella, Mkhitaryan, Dimarco; Arnautovic, Thuram
Barcelona: Szczesny; Garcia, Araujo, Cubarsi, Martinez; Pedri, De Jong; Yamal, Olmo, Raphinha; Lewandowski

Inter Milan v Barcelona Betting Tips

✅ Inter Milan to Qualify – 2.18
✅ Marcus Thuram to Score Anytime – 2.80
Under 2.5 Total Goals – 2.80

Bet on Inter Milan v Barcelona
Odds correct at time of writing

Stephen is our resident Irishman who has been playing or watching sports in Ireland for nearly two decades. With more than 10 years of experience as a professional writer, Stephen enjoys exploring all aspects of sports to offer the best…

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